Top Introduction of Cancer in Situ 2023
Cancer in situ is a term that describes a group of abnormal cells that are confined to the place where they originated and have not invaded or spread to other tissues. Cancer in situ is also known as stage 0 cancer, non-invasive cancer, or pre-cancer. Cancer in situ can affect different types of cells in the body, such as epithelial cells that line the skin, breast ducts, cervix, colon, bladder, prostate, and lungs. Depending on the tissue type and location, cancer in situ may have different names, such as cervical squamous intraepithelial lesion (SIL), ductal carcinoma in situ (DCIS) of the breast, Bowen’s disease of the skin, colon polyps, high-grade prostatic intraepithelial neoplasia (PIN), or bronchioloalveolar carcinoma (BAC) of the lung.
Cancer in situ is diagnosed by examining the cells under a microscope and looking for signs of abnormality, such as changes in size, shape, number, or arrangement. Cancer in situ differs from invasive cancer in that it has not broken through the basement membrane, which is a thin layer of tissue that separates the epithelial cells from the underlying connective tissue. Cancer in situ is considered to be at risk of becoming invasive cancer if left untreated, but the rate and likelihood of progression vary depending on the type and location of cancer in situ.
The treatment and prognosis of cancer in situ depend on several factors, such as the type and location of cancer in situ, the patient’s age and health status, and the patient’s preferences and goals. Some common treatment options for cancer in situ include surgery, radiation therapy, chemotherapy, hormone therapy, immunotherapy, or watchful waiting. The aim of treatment is to remove or destroy the abnormal cells and prevent them from becoming invasive cancer.
Cancer in situ is an important finding that can help detect and prevent invasive cancer at an early stage. However, not all cancers have a stage of cancer in situ, and not all cancers in situ will progress to invasive cancer. Therefore, it is important to consult with a doctor and follow the recommended screening and follow-up guidelines for each type of cancer.